When testosterone is too low

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What is hypogonadism due to certain medical conditions?

Hypogonadism, also known as Low Testosterone, can be caused by certain medical conditions that create a problem with the testes and/or parts of the brain that regulate the testes.

Possible Causes of Primary Hypogonadism:

  • Undescended or absent testes
  • Injury resulting in loss of testes
  • Inflammation of the testes
  • Surgical removal of testes
  • Genetic abnormalities, such as Klinefelter’s syndrome, in which males have an extra "X" chromosome
  • Chemotherapy that causes loss of normal testicular function
  • Damage to the testes from alcohol or heavy metals

Possible Causes of Secondary Hypogonadism:

  • Genetic abnormalities that result in abnormal function of the hormones from the brain and pituitary that control the testes
  • Tumor, trauma, or radiation that involve the pituitary gland's control of the testes

How testosterone is produced in the body, and what causes low levels Testosterone levels between 300 ng/dL and 1000 ng/dL are generally considered in the normal range. The brain and the testes work together to keep testosterone in this range. When levels of testosterone are below the normal range, the brain signals the testes to make more. When there is enough testosterone, the brain signals the testes to make less.

Only your doctor can determine if you have an underlying medical condition that is causing your testosterone levels to remain too low. So if you have been diagnosed with hypogonadism due to a certain medical condition, you and your doctor should work together to determine if treatment is right for you. AndroGel 1.62% is one treatment option that, through daily morning use, may raise the testosterone levels of appropriate patients. It should not be used in adult men who have low testosterone as a result of aging alone or in children under the age of 18.

Key points

  • The brain and testes work together to maintain a normal level of testosterone.
  • Hypogonadism can occur when a man has low testosterone levels which can be caused by certain medical conditions that create a problem affecting the testes and/or parts of the brain that regulate the testes.
  • Today, men with hypogonadism due to certain medical conditions may be able to raise their testosterone levels and keep them in the normal range.
Have questions? We have answers. Call our hotline at 1-855-AGEL-1621-855-AGEL-162.

Hypogonadism caused by certain medical conditions is treatable.

USE: AndroGel® (testosterone gel) 1% and 1.62%

AndroGel® (testosterone gel) 1% and 1.62% are controlled substances, available by prescription, used to treat adult males who have low or no testosterone due to certain medical conditions. It is not known if AndroGel is safe or effective to treat men who have low testosterone due to aging. It is not known if AndroGel is safe or effective in children younger than 18 years old. Testosterone products that are applied to the skin may have different doses, strengths, or application instructions that may lead to different levels of testosterone in your body.

Important Safety Information

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088or call 1-800-FDA-1088.

If you cannot afford your medication, contact www.pparx.org for assistance.

Click here for Use and Important Safety Information.

References: 1. AndroGel 1.62% [package insert]. North Chicago, IL: AbbVie Inc. 2. AndroGel 1% [package insert]. North Chicago, IL: AbbVie Inc.