Differences between
AndroGel 1.62% and AndroGel 1%

AndroGel 1.62% and AndroGel 1%

There are several meaningful differences between AndroGel 1.62% and AndroGel 1%. AndroGel 1.62% offers patients a more concentrated formulation of testosterone than AndroGel 1%.

Talk with your doctor to know which one is right for you.

AndroGel 1.62%

AndroGel 1%

Packaging options Pump
and packets
Packets only
Amount of daily gel at starting dose 2.5 g of gel
(40.5 mg)
5 g of gel
(50 mg)
Application sites 2 application sites (shoulders and upper arms) 4 application sites (shoulders, upper arms, and/or stomach area)

It is important to note:

AndroGel can transfer from your body to others. This can happen if other people come into contact with the area where the AndroGel was applied. Signs of puberty that are not expected have happened in young children who were accidentally exposed to testosterone through skin-to-skin contact with men using topical testosterone products like AndroGel. Women and children should avoid contact with the unwashed or unclothed area where AndroGel has been applied.

Facts about AndroGel 1%

Patients currently on AndroGel 1%

For those patients still on AndroGel 1%, you should know that there is a more concentrated version available—AndroGel 1.62%. If you’re interested in using less gel, talk to your doctor about AndroGel 1.62% today. If you’d like more information on AndroGel 1%, just read on below and then discuss the information with your doctor.

What is AndroGel 1%?

AndroGel 1% is a controlled substance (CIII), available by prescription, used to treat adult men with low or no testosterone due to certain medical conditions. It is not known if AndroGel 1% is safe or effective to treat men who have low testosterone due to aging. It is a daily testosterone replacement therapy (TRT) that can raise low testosterone levels with daily use. The testosterone in AndroGel 1% is the same as the testosterone that your body makes naturally. And, when used daily, it can help you raise your testosterone levels.

AndroGel 1% is clear, odorless, and quick-drying. And it is available in pre-measured packets. AbbVie no longer manufactures the AndroGel 1% pump for US markets. If you’re currently using the AndroGel 1% pump, talk to your healthcare provider about alternatives, including AndroGel 1% packets, the AndroGel 1.62% pump, and AndroGel 1.62% packets. For more information, call 1-800-633-9110 or visit abbviemedinfo.com.

It is important to note:

AndroGel 1% can transfer from your body to others. This can happen if other people come into contact with the area where the AndroGel 1% was applied. Signs of puberty that are not expected have happened in young children who were accidentally exposed to testosterone through skin-to-skin contact with men using topical testosterone products like AndroGel 1%. Women and children should avoid contact with the unwashed or unclothed area where AndroGel 1% has been applied.

How does AndroGel 1% work?

AndroGel 1% contains testosterone, which is absorbed through the skin after application. The testosterone in AndroGel 1% is the same as the testosterone your body makes naturally. It can help raise testosterone levels to the normal range in most men when used daily.

The most common side effects of AndroGel 1% are acne, skin irritation where the gel is applied, increased cholesterol levels, increased prostate specific antigen (a test used to screen for prostate cancer), increased red blood cell count, and increased liver function tests.

AndroGel 1% clinical study results

In a clinical study, of the 129 hypogonadal men who continued AndroGel 1% therapy for 6 months (with the dose adjusted properly), 87% had their testosterone levels restored to normal.

Safety information
AndroGel 1% can cause serious side effects, including worsening symptoms of an enlarged prostate; possible increased risk of prostate cancer; blood clots in the legs or lungs; possible increased risk of heart attack or stroke; lower sperm count; swelling of ankles, feet, or body; enlarged or painful breasts; and problems breathing during sleep. Before you use AndroGel, tell your doctor if you have breast cancer; prostate cancer; urinary problems due to enlarged prostate; heart, kidney, or liver problems; problems breathing while you sleep (sleep apnea); or any other medical conditions.

Before you begin treatment with AndroGel 1%

AndroGel 1% is a topical testosterone replacement therapy. Since AndroGel 1% is a gel, there are a few things you should know about packaging and application before you begin treatment.

AndroGel 1% packaging

AndroGel 1% is available in packets. The pre-measured packets contain enough gel for a single application for certain doses.

Your individual dosage may vary, so be sure to follow your doctor’s instructions.

AbbVie no longer manufactures the AndroGel 1% pump for US markets. If you’re currently using the AndroGel 1% pump, talk to your healthcare provider about alternatives, including AndroGel 1% packets, the AndroGel 1.62% pump, and AndroGel 1.62% packets. For more information, call 1-800-633-9110 or visit abbviemedinfo.com.

AndroGel 1% application instructions

It is important that you understand the correct way to apply AndroGel 1%. Read below to find application information.

  1. Apply AndroGel 1% at the same time each morning. AndroGel 1% should be applied after showering or bathing to clean, dry, intact skin.
  2. Your healthcare provider will tell you how much AndroGel 1% to apply. AndroGel 1% is available in packets. Each packet contains 25 mg of testosterone in 2.5 g of gel or 50 mg of testosterone in 5 g of gel. Open them by tearing along the dotted line. Squeeze the contents into the palm of your hand. Squeeze from the bottom of the packet up. AndroGel 1% should be applied right away.
  3. Apply the gel to one or more of the application sites. These areas are your shoulders and upper arms, and/or stomach area. Do not apply AndroGel 1% to any other parts of your body, such as your penis, scrotum, chest, armpits (axillae), knees, or back.
  4. Repeat steps 2 and 3 until you have applied the dose your doctor has prescribed for you.

After you apply AndroGel 1%

  • Wash your hands right away with soap and water.
  • Let the application sites dry.
  • Cover the application sites with a T-shirt.

When using AndroGel 1% it is important to note the following.

AndroGel 1% is flammable until dry. Let the gel dry before smoking or going near an open flame.

Avoid showering, swimming, or bathing for at least 5 hours after you apply AndroGel 1%.

Women and children should avoid contact with the unwashed or unclothed area where AndroGel 1% has been applied. If a woman or child makes contact with the AndroGel 1% application area, the contact area on the woman or child should be washed well with soap and water right away. Stop using AndroGel 1% and call your healthcare provider right away if you see any signs and symptoms of puberty in a child, or changes in body hair or increased acne in a woman, that may have occurred through accidental exposure to AndroGel 1%.

Your healthcare provider may change your AndroGel 1% dose. Do not change your AndroGel 1% dose without talking to your healthcare provider.

AndroGel 1% is not meant for use in women.

About the AndroGel 1% pump

The AndroGel 1% pump is no longer being manufactured. Seek your doctor's advice on how to move forward, whether it be with the AndroGel 1.62% pump, AndroGel 1.62% packets, or AndroGel 1% packets. For more information, call 1-800-633-9110 or visit abbviemedinfo.com.

About the AndroGel 1% packets

AndroGel 1% is available in packets. Each packet contains 25 mg of testosterone in 2.5 g of gel or 50 mg of testosterone in 5 g of gel. After use, throw away the packet in the trash out of the reach of children to avoid accidental exposure.

Safety considerations for AndroGel 1% and AndroGel 1.62%

AndroGel can transfer from your body to others. This can happen if other people come into contact with the area where the AndroGel was applied. Strict adherence to the following precautions is advised in order to minimize the potential for secondary exposure to testosterone from AndroGel-treated skin:

  • Children and women should avoid contact with unwashed or unclothed application site(s) of men using testosterone gel.
  • Patients should wash their hands right away with soap and water after application.
  • Cover the application site(s) with clothing after the gel has dried.
  • Wash the application site(s) thoroughly with soap and water prior to any situation where skin-to-skin contact of the application site(s) with another person is anticipated.
  • In the event that unwashed or unclothed application site(s) of men using AndroGel come in contact with a woman or child, the area of contact on the woman or child should be washed with soap and water right away.

Key points

  • AndroGel 1.62% is concentrated, so you can use less gel than AndroGel 1%.
  • Dosing and application sites for AndroGel 1.62% differ from AndroGel 1% and from other topical testosterone products.

USE: AndroGel® (testosterone gel) 1% and 1.62%

AndroGel® (testosterone gel) 1% and 1.62% are controlled substances, available by prescription, used to treat adult males who have low or no testosterone due to certain medical conditions. It is not known if AndroGel is safe or effective to treat men who have low testosterone due to aging. It is not known if AndroGel is safe or effective in children younger than 18 years old. Testosterone products that are applied to the skin may have different doses, strengths, or application instructions that may lead to different levels of testosterone in your body.

Important Safety Information

  • AndroGel can transfer from your body to others. This can happen if other people come into contact with the area where AndroGel was applied.
  • Signs of puberty that are not expected have happened in young children who were accidentally exposed to testosterone through skin-to-skin contact with men using topical testosterone products like AndroGel.
  • Women and children should avoid contact with the unwashed or unclothed area where AndroGel has been applied. If a woman or child makes contact with the AndroGel application area, the contact area on the woman or child should be washed well with soap and water right away.
  • To lower the risk of transfer of AndroGel 1.62%, you should apply it only to your shoulders and upper arms, areas that will be covered by a short-sleeve T-shirt. Do not apply AndroGel 1.62% to any other parts of your body, such as your stomach area (abdomen), penis, scrotum, chest, armpits (axillae), or knees. Wash your hands right away with soap and water after applying. After the gel has dried, cover the application area with clothing until you have washed the application area well or have showered. If you expect another person to have skin-to-skin contact with your shoulders or upper arms, first wash the application area well with soap and water.
  • To lower the risk of transfer of AndroGel 1%, you should apply it only to areas that will be covered by a short-sleeve T-shirt. These areas include shoulders, upper arms, and stomach area. Do not apply AndroGel 1% to any other parts of your body, such as your penis, scrotum, chest, armpits (axillae), knees, or back. Wash your hands right away with soap and water after applying AndroGel. After the gel has dried, cover the application area with clothing. If you expect to have skin-to-skin contact with another person, first wash the application area well with soap and water.
  • Stop using AndroGel and call your healthcare provider right away if you see any signs and symptoms of puberty in a child, or changes in body hair or increased acne in a woman, that may have occurred through accidental exposure to AndroGel.
  • Do not use AndroGel if you have breast cancer or have or might have prostate cancer.
  • AndroGel is not meant for use in women and must not be used in women who are or may become pregnant or are breastfeeding. AndroGel may harm the unborn or breastfeeding baby. Women who are pregnant or who may become pregnant should avoid contact with the area of skin where AndroGel has been applied.
  • Before you use AndroGel, tell your healthcare provider if you have breast cancer; prostate cancer; urinary problems due to enlarged prostate; heart, kidney, or liver problems; problems breathing while you sleep (sleep apnea); or have any other medical conditions.
  • AndroGel can cause serious side effects, including:
    • If you already have enlargement of your prostate gland, your signs and symptoms can get worse while using AndroGel (including changes in urination)
    • Possible increased risk of prostate cancer
    • Blood clots in the legs or lungs. Signs and symptoms of a blood clot in your leg can include leg pain, swelling, or redness. Signs and symptoms of a blood clot in your lungs can include difficulty breathing or chest pain.
    • Possible increased risk of heart attack or stroke
    • In large doses, AndroGel may lower your sperm count
    • Swelling of your ankles, feet, or body, with or without heart failure. This may cause serious problems for people who have heart, kidney, or liver disease
    • Enlarged or painful breasts
    • Having problems breathing while you sleep (sleep apnea)
  • Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take insulin, medicines that decrease blood clotting, or corticosteroids.
  • AndroGel is flammable until dry. Let AndroGel dry before smoking or going near an open flame.
  • The most common side effects of AndroGel 1.62% are increased prostate specific antigen (a test used to screen for prostate cancer), mood swings, high blood pressure, increased red blood cell count, and skin irritation where the gel is applied. The most common side effects of AndroGel 1% are acne, skin irritation where the gel is applied, increased cholesterol levels, increased prostate specific antigen, increased red blood cell count, and increased liver function tests.
  • AndroGel 1% and 1.62% application sites and dosages are not interchangeable with each other or with other topical testosterone products.
  • This is the most important information to know about AndroGel. For further information, talk with your healthcare provider.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088or call 1-800-FDA-1088.

If you cannot afford your medication, contact www.pparx.org for assistance.

References: 1. AndroGel 1.62% [package insert]. North Chicago, IL: AbbVie Inc. 2. AndroGel 1% [package insert]. North Chicago, IL: AbbVie Inc.