How AndroGel 1.62% works

Results of treatment with AndroGel 1.62%

In a clinical study of 274 men who had low testosterone, some used AndroGel 1.62% and some used placebo. Of the men who used AndroGel 1.62% once daily for 16 weeks, 82% had their testosterone levels returned to normal compared to 37% of those who used placebo.

The most common side effects of AndroGel 1.62% are increased prostate specific antigen (a test used to screen for prostate cancer), mood swings, high blood pressure, increased red blood cell count, and skin irritation where the gel is applied.

How does AndroGel 1.62% work?

AndroGel 1.62% contains testosterone, which is absorbed through the skin after application. The testosterone in AndroGel 1.62% is the same as the testosterone your body makes naturally. It can help raise testosterone levels to the normal range in most men when used daily.

Safety Considerations

AndroGel 1.62% can cause serious side effects, including worsening symptoms of an enlarged prostate; possible increased risk of prostate cancer; blood clots in the legs or lungs; possible increased risk of heart attack or stroke; lower sperm count; swelling of ankles, feet, or body; enlarged or painful breasts; and problems breathing during sleep. Before you use AndroGel, tell your doctor if you have breast cancer; prostate cancer; urinary problems due to enlarged prostate; heart, kidney, or liver problems; problems breathing while you sleep (sleep apnea); or have any other medical conditions.

Key points

  • AndroGel 1.62% is absorbed through the skin after application.
  • In a clinical study, most men treated with AndroGel 1.62% had their testosterone levels restored to normal.
  • AndroGel 1.62% is not a cure for hypogonadism due to certain medical conditions. It's a gel that you must use routinely, as you would take a daily medication.
  • AndroGel 1.62% can cause serious side effects.
USE: AndroGel® (testosterone gel) 1% and 1.62%

AndroGel® (testosterone gel) 1% and 1.62% are controlled substances, available by prescription, used to treat adult males who have low or no testosterone due to certain medical conditions. It is not known if AndroGel is safe or effective to treat men who have low testosterone due to aging. It is not known if AndroGel is safe or effective in children younger than 18 years old. Testosterone products that are applied to the skin may have different doses, strengths, or application instructions that may lead to different levels of testosterone in your body.

Important Safety Information

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088or call 1-800-FDA-1088.

If you cannot afford your medication, contact www.pparx.org for assistance.

Click here for Use and Important Safety Information.

Please see the full Prescribing Information for AndroGel on this website for more information.

References: 1. AndroGel 1.62% [package insert]. North Chicago, IL: AbbVie Inc. 2. AndroGel 1% [package insert]. North Chicago, IL: AbbVie Inc.